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Int J Biol Macromol ; 190: 520-532, 2021 Nov 01.
Artigo em Inglês | MEDLINE | ID: mdl-34480908

RESUMO

The abundance of two-dimensional (2D) components has provided them with a broad material platform for building nano and atomic-level applications. So, 2D nanomaterials are unique because of their physicochemical properties. Over many years, graphene is a conventional 2D layered element that has significant attention in the scientific community. In recent years numerous new 2D nanomaterials other than graphene have been reported. The study of 2D nanomaterials is also in its infant stages, with the majority of research focusing on the explanation of special material properties, but very few articles are focusing on the biological applications of 2D nanomaterials. As a result, we focused on the transition metal dichalcogenides (TMDCs) such as MoS2 and WS2, which were emerging and exciting groups of elements with display great opportunities in several fields, such as cancer nanomedicine. Herein, we synthesized biologically active CS/WS2/Ru composite by liquid exfoliation approach. The CS/WS2/Ru composites exhibit significant antibacterial action towards (S. aureus, and E. coli) bacteria. Also, the composite suggests synergetic anticancer action against MCF-7 cancer cells. These reports are possible to explore the innovative aspects of biological outcomes in carcinological applications.


Assuntos
Antibacterianos/farmacologia , Antineoplásicos/farmacologia , Quitosana/química , Química Verde , Nanocompostos/química , Nanopartículas/química , Rutênio/química , Sulfetos/química , Compostos de Tungstênio/química , Bactérias/efeitos dos fármacos , Morte Celular/efeitos dos fármacos , Forma Celular/efeitos dos fármacos , Humanos , Células MCF-7 , Testes de Sensibilidade Microbiana , Nanocompostos/ultraestrutura , Nanopartículas/ultraestrutura , Espectroscopia Fotoeletrônica , Espectrometria por Raios X , Espectrofotometria Ultravioleta , Espectroscopia de Infravermelho com Transformada de Fourier , Análise Espectral Raman , Propriedades de Superfície , Termogravimetria , Difração de Raios X
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